Histamine Receptor - 搜索结果

找到约 30 条 “Histamine Receptor” 相关结果（用时 0.167 秒）

目录号	产品名称	中文名称	靶点
M25486	(S)-(+)-Dimethindene maleate	(S)-(+)-Dimethindene maleate	AChR/AChE
	(S)-(+)-Dimethindene maleate 是一种有效的选择性毒蕈碱 M2 受体拮抗剂 (pA2 = 7.86/7.74; pKi = 7.78)。(S)-(+)-Dimethindene maleate 也是一种组胺 H1 受体 (histamine H1 receptor) 拮抗剂 (pA2 = 7.48)。
M2639	Dimaprit dihydrochloride	Dimaprit dihydrochloride	Histamine Receptor
	Dimaprit is a histamine type 2 receptor agonist.
M2643	Diphenylpyraline hydrochloride	盐酸二苯比拉林；双苯比拉林盐酸盐	Histamine Receptor
	4-Diphenylmethoxy-1-methylpiperidine hydrochloride
	Diphenylpyraline hydrochloride (DPP) is an internationally available antihistamine that produces therapeutic antiallergic effects by binding to histamine H₁ receptors.
M2671	Epinastine hydrochloride	依匹斯汀盐酸盐	Histamine Receptor
	WAL801 hydrochloride
	Epinastine HCl是一种抗组胺剂和肥大细胞稳定剂。Epinastine hydrochloride 是一种有效的，选择性的，具有口服活性的组胺 H1 受体 (histamine H1 receptor) 拮抗剂。
M2784	JNJ-7777120	JNJ-7777120	Histamine Receptor
	JNJ-7777120是第一个，有效的，选择性非咪唑histamine H4 receptor拮抗剂，K_i为4.5 nM，比作用于其他组胺受体选择性高1000倍以上。
M5752	Loratadine	氯雷他定	Histamine Receptor
	SCH29851
	Loratadine是一种选择性的histamine H1 receptor拮抗剂，用于治疗过敏。同时还是一种选择性的B(0)AT2抑制剂，其IC50为 4 μM。
M7722	Ciproxifan hydrochloride	环丙基[4-[3-(1H-咪唑-5-基)丙氧基]苯基]甲酮盐酸盐	Others
	Ciproxifan（CPX） belongs to a novel chemical series of histamine H₃-receptor antagonists.
M7849	Imetit dihydrobromide	IMETIT氢溴酸盐	Others
	Potent and selective H₃ histamine receptor agonist.
M7856	Immepip dihydrobromide	Immepip dihydrobromide	Others
	Immepip is a H₃ and H₄ histamine receptor agonist.
M7888	Levocabastine hydrochloride	左旋多巴	Others
	Non-peptide histamine H₁receptor antagonist; neurotensin NTS₂ receptor ligand.
M8229	Conessine	地麻素；康丝碱；可内新；抗痢夾竹桃鹼；錐絲鹼；锥丝碱；止泻木碱	Others
	Conessine is a plant steroid alkaloid that acts as a potent and specific antagonist of histamine H₃ receptors (Ki = 5.
M8795	Thioperamide maleate salt	Thioperamide maleate salt	Others
	Potent and selective H₃ histamine receptor antagonist that crosses the blood-brain barrier.
M8821	Triprolidine hydrochloride	盐酸曲普利啶	Others
	H₁ histamine receptor antagonist.
M9172	Emedastine Difumarate	富马酸依美斯汀	Histamine Receptor
	Rapimine
	Emedastine Difumarate is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity.
M9290	S 38093	S 38093	Histamine Receptor
	S38093
	S 38093是一种组胺H3受体（histamine H3 receptors）的反向激动剂，对大鼠，小鼠和人H3受体显示出中等亲和力，Ki值分别为8.8，1.44和1.2 μM。
M10391	Osthole	蛇床子素	Histamine Receptor
	Osthol; NSC 31868
	蛇床子素Osthole (Osthol) 是一种天然抗组胺试剂，可有效抑制组胺 H1 受体 (histamine H1 receptor) 的活性。
M11287	JNJ-39758979	JNJ-39758979	Histamine Receptor
	JNJ-39758979是一种选择性的、具有口服活性的、高亲和力的组胺 H4 受体 (histamine H4 receptor) 拮抗剂，对人，小鼠，猴子的组胺 H4 受体的 Ki 值分别为 12.5、5.3 和 25 nM。JNJ-39758979 对组胺诱导的 cAMP 抑制作用具有拮抗作用，pA2 为 7.9。JNJ-39758979 具有良好的抗炎、止痒作用。
M13991	Bepotastine	贝托司汀；贝他斯汀；贝托斯汀；贝他司汀	Histamine Receptor
	Bepotastine 是一种选择性的具有口服活性的第二代组胺 H1 受体 (histamine H1 receptor) 拮抗剂。Bepotastine 可用于过敏性鼻炎，过敏性结膜炎和荨麻疹/瘙痒症的研究。
M20424	CarbinoxaMine Maleate	CarbinoxaMine Maleate	Histamine Receptor
	Carbinoxamine maleate is a histamine-H1 receptor blocking agent with antihistamine and anticholinergic properties.
M20511	Betahistine	Betahistine	Histamine Receptor
	Betahistine Dihydrochloride is a histamine H3 receptors inhibitor used as an antivertigo drug.
M20513	Hydroxyzine pamoate	Hydroxyzine pamoate	Others
	Hydroxyzine pamoate, a derivative of hydroxyzine, is a histamine H1-receptor antagonist that has been used as anxiolytic and antihistaminic so that it is probably effective in the treatment of insomnia and withdrawal treatment.
M20515	Emedastine	Emedastine	Histamine Receptor
	Emedastine is a potent, high affinity histamine H1-receptor-selective antagonist with Ki of 1.3 ±0.1 nM for H1-receptors while considerably weaker at H2- (K1 = 49,067 ± 11,113 nM) and H3-receptors (Ki = 12,430 ± 1,282 nM).
M20518	Orphenadrine Hydrochloride	Orphenadrine Hydrochloride	Others
	A muscarinic receptor antagonist, specifically an H1 histamine receptor antagonist. This compound is a muscle relaxant. Orphenadrine has also been reported to inhibit the noradrenergic transporter and to block the NMDA receptor ion channel.
M20520	Chloropyramine hydrochloride	Chloropyramine hydrochloride	Histamine Receptor
	Halopyramine hydrochloride
	Chloropyramine hydrochloride is a histamine receptor H1 antagonist and has anti-cholinergic, antispasmodic, and antiallergic effects.
M20782	Pimethixene maleate	Pimethixene maleate	5-HT Receptor
	Pimetixene maleate
	Pimethixene (Pimetixene) maleate is a highly potent antagonist of a broad range of monoamine receptors, inhibits 5-HT2A, 5-HT2B, 5-HT2C, 5-HT1A, 5-HT1B, 5-HT6, 5-HT7, Adrenergic α-1A, Dopamine D1 Receptor, Dopamine D2 Receptor, Dopamine D4.4 Receptor, Histamine H1 Receptor, Muscarinic M1 and Muscarinic M2.
M20813	Cyclizine	Cyclizine	Histamine Receptor
	Cyclizine is a piperazine first-generation antagonist of histamine 1 receptor.
M20927	Betahistine mesylate	Betahistine mesylate	Histamine Receptor
	Betahistine mesylate is the mesylate salt form of Betahistine, a histamine analog and H3 receptor agonist that serves as a vasodilator.
M20988	Promethazine	Promethazine	Histamine Receptor
	Promethazine is a potent histamine H1 receptor antagonist. Promethazine is a medication used in the management and treatment of allergic conditions, nausea and vomiting, motion sickness, and sedation. Promethazine exhibits antiparasitic properties.
M20991	Levocetirizine	Levocetirizine	Histamine Receptor
	LCZ, (R)-Cetirizine
	Levocetirizine (LCZ, (R)-Cetirizine), the R-enantiomer of cetirizine, is an antagonist of histamine H(1) receptor.
M27613	Irdabisant hydrochloride	Irdabisant hydrochloride	Histamine Receptor
	CEP-26401 hydrochloride
	Irdabisant (CEP-26401) hydrochloride 是一种具有选择性、口服活性和血脑屏障渗透性的组胺 H3 受体 (histamine H3 receptor, H3R) 拮抗剂/逆激动剂，对大鼠 H3R 和人 H3R 的 Ki 分别为 7.2 nM 和 2.0 nM。Irdabisant hydrochloride 对 hERG 电流的抑制活性相对较低，IC50 为 13.8 μM。

信号通路

产品类型

AbMole

服务与支持

技术资源

联系我们